Neurodystrophic hypothesis posits that neural dysfunction leads to what effect on tissues?

Neurodystrophic hypothesis posits that neural dysfunction leads to what effect on tissues?

• A. Increased tissue resistance
• B. No relation to tissue resistance
• C. Lowered tissue resistance due to systemic stress on viscera
• D. Localized tissue thickening

Answer: (C)

Neural dysfunction alters tissue trophic function, so tissues lose their normal resilience and resistance to disease. In the neurodystrophic view, disrupted nerve signaling—especially autonomic input—changes blood flow, nutrition, and immune responses in tissues. When systemic stress on the viscera is present, this autonomic disturbance can contribute to a broader decrease in tissue resistance, making tissues more susceptible to pathology. Increased tissue resistance or no relation to tissue resistance would contradict the idea that nerve dysfunction compromises tissue health, and localized thickening implies a specific, localized change rather than a generalized decrease in resistance.

Neural dysfunction alters tissue trophic function, so tissues lose their normal resilience and resistance to disease. In the neurodystrophic view, disrupted nerve signaling—especially autonomic input—changes blood flow, nutrition, and immune responses in tissues. When systemic stress on the viscera is present, this autonomic disturbance can contribute to a broader decrease in tissue resistance, making tissues more susceptible to pathology. Increased tissue resistance or no relation to tissue resistance would contradict the idea that nerve dysfunction compromises tissue health, and localized thickening implies a specific, localized change rather than a generalized decrease in resistance.