Which concept describes that neural dysfunction may cause lowered tissue resistance?

Which concept describes that neural dysfunction may cause lowered tissue resistance?

• A. Nerve compression theory
• B. Axoplasmic transport
• C. Neurodystrophic hypothesis
• D. Facilitation

Answer: (C)

Neural dysfunction can alter how tissues resist stress by changing local nervous system control and the inflammatory environment around the tissue. The neurodystrophic hypothesis says that when nerve function at a given segment is impaired, the tissues supplied by those nerves undergo physiologic changes that lower their resistance to insult, infection, and damage. This helps explain how a relatively small neural disturbance can lead to tissue irritability, altered blood flow, edema, and slower healing, all of which reflect reduced tissue resistance. The other concepts describe different ideas—nerve compression emphasizes mechanical pressure on a nerve, axoplasmic transport is about the movement of materials within the neuron, and facilitation focuses on reflex hyperexcitability—that don’t specifically account for neural dysfunction driving a drop in tissue resistance.

Neural dysfunction can alter how tissues resist stress by changing local nervous system control and the inflammatory environment around the tissue. The neurodystrophic hypothesis says that when nerve function at a given segment is impaired, the tissues supplied by those nerves undergo physiologic changes that lower their resistance to insult, infection, and damage. This helps explain how a relatively small neural disturbance can lead to tissue irritability, altered blood flow, edema, and slower healing, all of which reflect reduced tissue resistance. The other concepts describe different ideas—nerve compression emphasizes mechanical pressure on a nerve, axoplasmic transport is about the movement of materials within the neuron, and facilitation focuses on reflex hyperexcitability—that don’t specifically account for neural dysfunction driving a drop in tissue resistance.